Healthcare Services

This open access book explores the field of life science business from a multidisciplinary perspective. Applying statistical, mathematical, game-theoretic, and data science tools to pharmaceutical and biotechnology business endeavors, the book describes value creation, value maintenance, and value realization in the life sciences as a sequence of processes using the quantitative language of applied mathematics. Written by experts from a variety of fields, the contributions illustrate the shift from a deterministic to a stochastic view of the processes involved, offering a new perspective on life sciences economics. The book covers topics such as valuing and managing intellectual property in life science, licensing in the pharmaceutical business, outsourcing pharmaceutical R&D, and stochastic modelling of a pharmaceutical supply chain. The book will appeal to scholars of economics and the life sciences, as well as to professionals in chemical and pharmaceutical industries.

Stephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states.Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology.This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity,blood dynamics and bone mechanics.Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics etc. To benefit from this book, the readers are expected to have a background in general physiology and mathematics

Hardlopen is een van de meest populaire sporten ter wereld. Het is tevens een effectieve manier om de gezondheid te verbeteren of te onderhouden. Het vermindert de kans op hart- en vaatziektes, obesitas, diabetes type II en osteoporose. De keerzijde is echter dat hardlopers vaak blessures krijgen.Dit boek beschrijft veelvoorkomende hardloopblessures. Besproken worden onder andere diverse stressfracturen, compartimentsyndroom, mediaal tibiaal stresssyndroom, verschillende oorzaken van hielpijn, tarsaletunnelsyndroom, enkeldistorsie, iliotibiale bandsyndroom, het patellofemoraal pijnsyndroom, patellapeestendinose, achillespeestendinose, meniscuslaesie, hamstringblessure, compartimentsyndroom en verschillende circulatiestoornissen.Zoals gebruikelijk in de boekenreeks van Orthopedische Casuïstiek wordt ieder onderwerp besproken aan de hand van patiëntencasuïstiek uit de dagelijkse praktijk.De tekst is rijk geïllustreerd met educatieve tekeningen en foto's. De bijlagen achterin het boek tonen overzichten van de 'Ottawa Ankle Rules' en een overzicht van moeilijk te differentiëren aandoeningen van het onderbeen inclusief symptomatologie.Het boek is in het bijzonder bestemd voor (sport)fysiotherapeuten, kinesitherapeuten, verzorgers van een atletiekvereniging, sportartsen, huisartsen en orthopeden.

Poster DIN A1

Leicht verständlich erklärt Ihnen das Buch Grundlagen sowie tiefgreifende Zusammenhänge zur Interpretation von pathologischen EKGs und zum Erkennen der häufigsten Krankheitsbilder und Rhythmusstörungen.<BR><BR>Das Buch ist Schritt für Schritt vom Einfachen zum Komplexen aufgebaut und deshalb für alle Ausbildungsstufen im Rettungsdienst geeignet. Lernziele am Beginn jedes Kapitels erklären Ihnen, was warum gelernt werden soll. Am Kapitelende sorgen Zusammenfassungen und Wiederholungsfragen, die jeweils in ''Basic'' und ''Advanced'' unterteilt sind, für die Vertiefung des Gelernten.<BR><BR>Praxistipps, zahlreiche Abbildungen und EKG-Beispiele stellen den Bezug zur Praxis her und bereiten Sie auf den nächsten Einsatz vor. Zahlreiche Übungsfälle mit ausführlich kommentierten Lösungen veranschaulichen die Inhalte und sind ideal zum Üben.<BR><BR>Praktisch: die herausnehmbare EKG-Karte - ideal zum Mitnehmen beim Einsatz oder zum Üben.<BR><BR>Neu in der 2. Auflage:<BR>- Neue EKG-Fallszenarien- EKG-Neuzeichnungen, Austausch von Abbildungen- Aktualisierung aller InhalteDas Buch eignet sich für:<BR>- Auszubildende Notfall- und Rettungssanitäter*in- Praktiker*innen im Rettungsdienst

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.

This book analyses the ability of technological advancements to represent, enhance, and empower multidisciplinarity in the context of Society 5.0. and next generation medicine. New technologies allow patients to communicate with medical personnel anytime, anywhere and shape the terrain of healthcare ecosystem at an unprecedented rate. Five main trends become apparent in this process: Hybrid care models combining virtual and in-person services, digitization of healthcare specialties, increased Artificial intelligence (AI) adoption, health systems moving to the cloud and advanced precision medicine.In its chapters the book dissects the important roles for technologies in areas such as digital twinning, big data, Internet of Things, AI, cyber-physical systems, blockchain technology to lead the healthcare digitalization envisioned in Society 5.0. Throughout the book the authors discuss how to incorporate these new technologies legally, ethically, safely, and securely and in keeping with the highest standards of human rights. It also advocates for the need for careful oversight and mindful allocation of resources and energy for sustainable development.This book, written by experts in the field from academia and industry, will appeal to researchers, healthcare professionals, policy makers, teachers and students interested in the ways healthcare is reorganized based on digital transformation efforts and the rethinking of care, including technologies.

Das Buch dient als kompaktes Nachschlagewerk für Rettungssanitäter, Notfallsanitäter und Notärzte, die im Einsatz, auf der Wache oder im Krankenhaus schnell das Wichtigste parat zu Krankheitsbildern, Diagnosen und Behandlung haben möchten. Dosierungen von Medikamenten und deren Kontraindikationen und Nebenwirkungen finden sie in Übersichten zusammengestellt, Algorithmen verdeutlichen auf schnell verständliche Weise ein standardisiertes Vorgehen bei zeitkritischen Notfallbildern.