Dictionaries & Reference

This concise, easy-to-read pocket guide offers medical trainees, researchers, and clinicians at every level the perfect resource on Evidence Based Medicine (EBM). Based on the author's many years of experience teaching EBM to medical students and medical residents at Columbia University, this handy title addresses not only all the basic concepts and issues in EBM, but also takes an example-based approach and is replete with numerous illustrations. This brief book provides readers with all the tools needed to tell the good from the bad in healthcare research. It discusses every type of study design, from the assessment of diagnostic tests to clinical trials and meta-analysis. The work also introduces readers to novel methods, such as the Bayesian analysis of clinical trials. In addition, to help readers better retain the information, the guide includes thought-provoking review questions and answers in an appendix. In all, Pocket Evidence-Based Medicine: A Survival Guide for Clinicians and Students is an ideal resource for anyone who encounters statistics in their studies or career, including clinicians, researchers, trainees in medicine and graduate students in a wide range of other disciplines

Stephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states.Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology.This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity,blood dynamics and bone mechanics.Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics etc. To benefit from this book, the readers are expected to have a background in general physiology and mathematics