Neurologie

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The book covers all aspects of immune-mediated diseases of the muscle and nerve, which are a group of complex diseases, whose diagnosis needs a team of specialists in the field of neuropathology, immunopathology, neurology, and rheumatology. Nerve and muscle biopsy evaluation is invaluable in distinguishing immune-mediated from etiologies and therefore, despite being invasive, pathological evaluation of nerve and muscle has stood the test of time. Chapters cover all the essential aspects of each disease entity viz. the pathogenesis, clinical features, diagnostic armamentarium, and guidelines for diagnosis and management. It is supplemented with full-colorful illustrations and photomicrographs for better comprehension. It includes a chapter highlighting the current progress in the field of immune-mediated myopathies and neuropathies as it is a rapidly evolving field with the addition of many new entities.This clinically oriented book serves as a primer for general histopathologists as well as a practice guide for neuropathologists. It is also relevant for neurologists and rheumatologists and encourages young medical students, residents, and research scholars in the field of neuropathology, neurology, and rheumatology to get involved in active research.

The Ultimate Handbook for Success on the Spectrum - Written by and for Autistic People!<BR><BR>I feel like everyone else got a handbook with all the answers, and I never got my copy. This is a common thought among autistic people, because society is built with neurotypical people in mind-but that handbook has finally arrived. Even better, it was written by an autism activist who is on the spectrum himself. <BR><BR>Autistic influencer Daniel M. Jones is an expert on living well on the spectrum. No matter what you're going through as someone with autism, Dan gets it-he's been there. He's here to explain everything he learned, and then some, in this instruction manual and memoir about life as an autistic person. Dan's book is packed with actionable advice that readers can immediately start putting into practice. You'll learn how to navigate common challenges, such as dating on the spectrum, holding down a job, or performing well in school. Best of all, you'll learn to improve your life while also empowering yourself. <BR><BR>Dan's honesty, self-awareness, and sheer knowledge of autism make for a down-to-earth and relatable read that anyone will enjoy. No matter where you are on the spectrum, you'll love this hilarious and comprehensive guide to living an excellent life as an autistic adult.

Dieses Buch beleuchtet Aspekte neuroinflammatorischer Erkrankungen bei Kindern und Jugendlichen sowie das Gebiet der Neuroinfektionen in der Pädiatrie. Verfasst von Experten aus führenden Universitätskliniken und Gesundheitszentren sowohl in den Industrieländern als auch in den Entwicklungsländern, verfolgt das praxisorientierte Werk einen problemorientierten Ansatz zu diesen speziellen Erkrankungen des Nervensystems im Kindesalter. Das Buch wurde aus dem Englischen mithilfe von Künstlicher Intelligenz unter Verwendung der DeepL-Software übersetzt. Die Kapitel sind ursprünglich im Werk Clinical Child Neurology erschienen, das von Mustafa A.M. Salih im Springer-Verlag herausgegeben wurde..

This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.

L¿autismo è una condizione umana in cui si presentano alcune caratteristiche particolari. La disabilità dell¿autismo spesso è generata dalla difficoltà di modulare queste caratteristiche individuali rispetto alle richieste/abitudini/convenzioni del mondo esterno costituito per il 99% da persone neurotipiche. Il fatto che le persone con autismo, nella maggior parte dei casi, restino sole non è una scelta bensì l¿esito di reiterati fallimenti di tentativo di incontrare l¿altro, di comunicare, di costruire amicizie e relazioni. In altri termini, le persone con autismo hanno desiderio di incontrare gli altri, di costruire relazioni amicali, di avere una fidanzata/un fidanzato, ma quello che manca è come farlo, la competenza, l'abilità, in breve: lo skill. Questo manuale è stato pensato per fornire una guida pratica e semplificata ai professionisti impegnati e formati in questo settore che conducono gruppi con persone con autismo di funzionamento più elevato (livello 1 di autismo secondo il DSM 5), in età adulta-tardo adolescenziale, una sorta di manuale di sopravvivenza sociale per insegnare alle persone autistiche alcune strategie che permettano loro di vivere meglio, con meno disagio, nell¿ambiente che le circonda. Dopo una prima parte introduttiva sui Disturbi dello Spettro Autistico e la teoria dei SST, viene proposto un vero e proprio schema di percorso-tipo di circa sei mesi con sedute una volta a settimana volto a migliorare le abilità sociali.

This book focuses on asymmetries in brain structure and their role in emotional functions (such as amygdala in emotional comprehension, the ventro-medial prefrontal cortex in the integration between cognition and emotion and in the control of emotional reactions, and the anterior insula in the experience of emotions).The idea of hemispheric asymmetries in emotional comprehension and expression was first proposed about a century after the first studies showing that the left hemisphere is dominant for language, but it quickly became very popular. Initial investigations considered the right and left hemispheres as single functional units, but in the last few years several researchers have focused attention on asymmetries in brain structures playing a critical role in specific components of emotional functions.Furthermore, interesting data have been obtained by studying emotional and behavioural disorders of patients with asymmetrical forms of frontal or temporal variants of fronto-temporal degeneration.Elaborating on these subjects requires, on the one hand, a consolidated understanding of how models concerning the relationships between emotions and hemispheric asymmetries evolved in time and, on the other hand, a sound interdisciplinary knowledge of psychology (nature, components and hierarchical organization of emotions) and neuroscience (neuroanatomy). This volume - intended for neurologists, neuroscientists and psychologists - pursues an organic and consistent approach to provide an overview of these complex and fascinating issues.

The central nervous system, which includes the brain and spinal cord, has a high metabolic demand. The physiology of the brain is such that it is easily affected by alterations in other systems, which in turn can compromise cerebral blood flow and oxygenation. Together the brain and spinal cord control the automatic function of our body systems. While other systems of body controls individual functions, central nervous system at the same time does many different functions, especially, controlling the function of other systems. This interaction between the brain and other systems is important when it comes to understanding how injuries to the brain can, at times, produce complications in remote organs or systems of the body, such as the lungs. This book explains the lesser-known crosstalks between acutely or chronically affected brain and lung, describing the pathophysiology of the lung following brain injury and discussing in detail the conflicts between the brain and lungs in relation to the tidal volumes, positive end-expiratory pressures, arterial carbon dioxide and oxygen levels, recruitment maneuvers and positioning, as well as potential therapeutic targets.

Dit boek laat zien hoe neuropsychologische problematiek kan interfereren bij psychotherapeutische behandeling. Door hier meer op te focussen, kun je effectiever behandelen en misdiagnostiek voorkomen. Het beschrijft welke problemen je kan tegenkomen bij de behandeling, en welke kennis van neuropsychologische stoornissen nodig is bij aanvang en tijdens de behandeling. Tevens biedt het boek praktische handvatten voor de behandeling in de klinische praktijk.De rol van neuropsychologie in de psychotherapie is opgebouwd uit drie delen. Het algemene gedeelte gaat over de relatie tussen psychotherapie en neurowetenschappen, over kwetsbaarheid en veerkracht en over ontwikkelingsneuropsychologische perspectieven. In het tweede praktijkgericht deel komen de meest voorkomende psychische en psychiatrische problemen aan de orde, zoals depressie, chronische vermoeidheid, posttraumatisch stressstoornissen, ADHD en somatische symptoomstoornissen. Ook leest u over de mogelijke inzet van E-health bij de behandeling van deze patiënten. Deel drie, het tweede praktijkgerichte deel, richt zich op de gevolgen van niet aangeboren hersenletsel (NAH), zoals de identiteit na een NAH, beperkte cognitieve stoornissen, emotionele problemen en gesprekstherapie na hersenletsel. Daarnaast komt ook de mogelijke inzet van E-health bij behandeling van NAH aan de orde.Het boek richt zich op psychologen, psychotherapeuten en psychiaters werkzaam in de ggz. Het boek is eveneens goed bruikbaar binnen de diverse ggz-opleidingen.

Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders).

Das Urheberrecht an bibliographischen und produktbeschreibenden Daten und an den bereitgestellten Bildern liegt bei Informazioni Editoriali, I.E. S.r.l., oder beim Herausgeber oder demjenigen, der die Genehmigung erteilt hat. Alle Rechte vorbehalten.

This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions.

Contents include: 'Biochemistry and molecular biology of neural lipids', 'Advances in lipid analysis/lipidomics', 'Metabolism and enzymology of glycerolipids', 'Lipid metabolism in brain development and aging', 'Cellular and subcellular localization of neural lipids', and much more.

This is the first book devoted to the study of the social and economic consequences of headache. Reducing the Burden of Headache analyses the financial cost of headache diseases, the disability and suffering they cause and the impact they have on the quality of life of the sufferers and their families.These are issues of major importance; migraine appears in the top 2 list of diseases ranked according to years lived with disability. Headache, in general, is thought to account for approximately 2% of all days lost from work. Of even greater importance is the impact on everyday life, studies have shown that migraine has a greater impact on the quality of life of sufferers than many other diseases generally considered to be more serious.This book describes and analyses the epidemiological data accumulated in the field and suggests guidelines and interventions aimed at improving healthcare for headache. Adoption of these suggestions combined with judicious use of existing resources and modern treatment options can lead to great improvements in the lives of headache sufferers world-wide.This book will be of interest to neurologists, general practitioners, epidemiologists, public health specialists, health service managers and all those interested in improving services and outcomes for sufferers of headache.