The Secret of Life

By early morning of 30 June 1860, a large crowd began to congregate in front of Oxford University's brand-new Museum of Natural History. The occasion was the annual meeting of the British Association for the Advancement of Science, and the subject of discussion was Charles Darwin's new treatise: fact or fiction?Darwin, a simultaneously reclusive and intellectually audacious squire from Kent, claimed to have solved "that mystery of mysteries", introducing a logical explanation of the origin of species-how they adapted, even transmogrified, through natural selection. At stake, on that summer's day of spirited debate, was the very foundation of modern biology, not to mention the future of the church. Without fear of exaggeration, Darwin's thesis would forever change our understanding of the life sciences and the natural world. And yet the author himself was nowhere to be found in the debate hall-instead, he was miles away, seeking respite from a spate of illnesses that had plagued him for much of his adult life.In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians. The result is a colourful portrait of the man, his friends and enemies and his seminal work, which resonates to this day.

Acclaimed medical historian Howard Markel traces the careers of two brilliant young doctors—Sigmund Freud, neurologist, and William Halsted, surgeon—showing how their powerful addictions to cocaine shaped their enormous contributions to psychology and medicine.<BR> <BR>When Freud and Halsted began their experiments with cocaine in the 1880s, neither they, nor their colleagues, had any idea of the drug's potential to dominate and endanger their lives. An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction. Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Here is the full story, long overlooked, told in its rich historical context.  

A FIRST-EVER COLLECTION FROM AMERICA'S MOST DISTINGUISHED HISTORIAN OF MEDICINE AND CULTURAL LIFE From Howard Markel, author of An Anatomy of Addiction "Absorbing, vivid" -- Sherwin Nuland, The New York Times Book Review, front page) and The Kelloggs (2017 National Book Critics Circle Award Finalist for Biography), Literatim is a collection of the writer's essays on medicine, American culture, and how their intersections compose the interstitial matter of modern life. Through topics ranging from illness to baseball to the lives of America's most beloved artists and performers, Markel's eye for the unexamined corners of contemporary life align with his singular storytelling ability for a collection that demonstrates how literature, like medicine, can be a portal to better understanding the human condition. Selected and with an introduction by the award-winning and bestselling author, Literatim gathers more than 80 essays, a thirty-year retrospective of Markel's work from 1987 to 2019. "Although writers and physicians use markedly different tools and approaches," he writes, "both are recording and interpreting narratives." Literatim is a stirring and entertaining testament to that persisting truth.