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High-Density Lipoproteins as Biomarkers and Therapeutic Tools

Volume 2. Improvement and Enhancement of HDL and Clinical Applications

Kyung-Hyun Cho
Englisch | Hardcover

This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

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Produktinformationen "High-Density Lipoproteins as Biomarkers and Therapeutic Tools"

This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

Untertitel
Volume 2. Improvement and Enhancement of HDL and Clinical Applications
H | B | T | Gramm
241 mm | 160 mm | 21 mm | 594 gr
Erscheinungsjahr
2019
FSK
0
Ausgabe
Hardcover
Verlag
Springer
ISBN-10
9811373825
ISBN-13
9789811373824
Autor
Kyung-Hyun Cho
Sprache
Englisch
Seitenanzahl
284
Themen
Krankheiten und Störungen, Biotechnologie, Medizinische Chemie, Pharmazeutische Chemie, Medizinische Forschung, Biotechnologie
Verantwortliche Person gemäß Art. 16 GPSR
Springer Nature Customer Service Center GmbH, Europaplatz 3, 69115, Heidelberg, DE, ProductSafety@springernature.com

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High-Density Lipoproteins as Biomarkers and Therapeutic Tools
High-Density Lipoproteins as Biomarkers and Therapeutic Tools
Kyung-Hyun Cho
This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

Buch | Englisch

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