Foundations and Emerging Perspectives in Human Blood Groups 

Human blood groups are among the most important discoveries in medical science, underpinning safe blood transfusion, organ transplantation, maternal-fetal medicine, and modern immunohematology. However, growing scientific evidence reveals that blood group antigens play far broader roles in human health and disease than previously recognized. Foundations and Emerging Perspectives in Human Blood Groups presents a comprehensive and authoritative examination of the scientific foundations, clinical applications, and emerging research frontiers of human blood group systems. Written by leading international experts, this volume bridges traditional immunohematology with contemporary advances in disease pathogenesis, transfusion medicine, healthcare policy, and precision medicine. The book explores the historical evolution of blood group science, the clinical significance of blood group antigens in transfusion practice, and their increasingly recognized roles in infectious diseases, autoimmune disorders, allergies, malignancies, and immune regulation. It also addresses practical challenges and evidence-based strategies for strengthening blood transfusion services and healthcare delivery systems, particularly in resource-limited settings. Combining scientific rigor with clinical relevance, this book provides an invaluable resource for transfusion medicine specialists, hematologists, immunologists, medical laboratory scientists, clinicians, researchers, healthcare policymakers, educators, and postgraduate students. As our understanding of blood group antigens continues to expand beyond transfusion compatibility, this volume offers fresh perspectives on their significance in disease, immunity, population health, and the future of patient care.